Table 1

Demographic characteristics and history of gynaecological surgeries for FDR, SDR and TDR of ovarian cancer cases and matched controls

FDR of case
(n=11 197)
n (%)
FDR of control
(n=117 591)n (%)
SDR of case
(n=32 524)
n (%)
SDR of control
(n=347 069)
n (%)
TDR of case
(n=86 059)
n (%)
TDR of control
(n=895 049)
n (%)
Follow-up duration (years)*†36.7±14.337.1±14.333.2±15.233.1±15.330.9±15.630.6±15.7
Birth year†1937.1±25.61938.8±26.51949.8±33.81952.0±33.81954.8±36.21956.2±36.4
Born in Utah†9602 (85.8)102 925 (87.5)29 843 (91.8)320 953 (92.5)80 084 (93.1)837 138 (93.5)
White10 817 (96.6)113 776 (96.8)30 929 (95.1)330 145 (95.1)80 896 (94.0)839 935 (93.8)
Non-Hispanic8798 (78.6)91 913 (78.2)24 025 (73.9)255 725 (73.7)62 626 (72.8)651 446 (72.8)
Nulliparous*781 (7.0)8039 (6.8)1987 (6.1)20 758 (6.0)1046 (1.2)10 328 (1.2)
Ever tubal ligation*229 (2.0)2354 (2.0)1098 (3.4)10 704 (3.1)2368 (2.8)23 659 (2.6)
Ever hysterectomy*1022 (9.1)9144 (7.8)2440 (7.5)25 348 (7.3)4949 (5.8)50 288 (5.6)
Ever bilateral oophorectomy*843 (7.5)5614 (4.8)1385 (4.3)13 035 (3.8)2696 (3.1)26 481 (3.0)
Ever bilateral salpingectomy*835 (7.5)5722 (4.9)1431 (4.4)13 668 (3.9)2807 (3.3)27 706 (3.1)
Ever diagnosed with ovarian cancer*120 (1.1)735 (0.6)206 (0.6)1387 (0.4)476 (0.6)3576 (0.4)
  • *From start of follow-up to the end of 2016.

  • †Matching factor for case probands and controls.

  • FDR, first-degree relative; SDR, second-degree relative; TDR, third-degree relative.