A gene-based analysis of SNPs associated with atrial fibrillation/flutter in the consensus Xp22.31 deletion interval in males (4556 cases vs 163 499 controls) and females (2144 cases vs 193 494 controls) from the UK Biobank
| Gene | Start (bp) | Stop (bp) | Males | Females | ||||
| NSNPs | NParam | P value | NSNPs | NParam | P value | |||
| VCX3A | 6 451 659 | 6 453 159 | 5 | 3 | 0.229 | 5 | 3 | 0.745 |
| HDHD1 | 6 966 961 | 7 066 231 | 225 | 12 | 0.061 | 223 | 13 | 0.983 |
| STS | 7 065 298 | 7 272 682 | 343 | 20 | 0.041* | 336 | 20 | 0.793 |
| VCX | 7 810 303 | 7 812 184 | 4 | 2 | 0.639 | 3 | 2 | 0.259 |
| PNPLA4 | 7 866 804 | 7 895 780 | 39 | 6 | 0.633 | 39 | 6 | 0.278 |
| VCX2 | 8 137 985 | 8 139 308 | 11 | 4 | 0.444 | 8 | 3 | 0.444 |
*P<0.05.
NParam, the number of relevant parameters used in the model (essentially the number of independent SNPs in the gene); NSNPs, the number of SNPs in the data annotated to the gene.