Age at the onset of VHL-related manifestations
| Manifestations | Mean±SD | Median (range) |
| CHB (59.1%) | 29.5±11.0 | 28.0 (10–66) |
| RA (19.9%) | 24.8±11.0 | 23.0 (2–55) |
| RCC (43.3%) | 36.4±10.9 | 34.0 (14–74) |
| PCL (40.6%) | 33.4±11.0 | 32.0 (10–66) |
| PHEO (13.4%) | 31.7±11.9 | 31.5 (8–66) |
| GS (6.5%) | 21.4±11.2 | 19.0 (4–56) |
CHB, central nervous system haemangioblastoma; GS, genital system (epididymis or broad ligament); PCL, pancreatic cystic lesion; PHEO, pheochromocytoma; RA, retinal haemangioblastoma; RCC, renal cell carcinoma; VHL, von Hippel-Lindau.