Costs associated with genetic testing for LS
| Costs for cohort (CHF) | Current strategy | Alternative strategy |
| IHC | 1 476 000 | 0 |
| BRAF V600E | 50 809 | 0 |
| DNA sequencing | 497 808 | 14 350 000 |
| DNA sequencing for relatives | 29 442 | 110 700 |
| Colonoscopy and treatment | 134 912 887 | 136 231 000 |
| Total | 136 966 947 | 150 691 700 |
| QALYs gained | 361 147 | 361 358 |
| Cost difference | 13 724 753 | |
| QALYs difference | 211 | |
| ICER | 65 058 | |
ICER, incremental cost-effectiveness ratio; IHC, immunohistochemistry; LS, Lynch syndrome; QALYs, quality-adjusted life years.