Table 1

Details of severe scoliosis cases with pathogenic FBN1 variants

n
Total number of patients57
Sex (%)
 Male20 (35.1)
 Female37 (64.9)
Details of ‘severe’ scoliosis
 Surgery conducted42
  Age at first surgery, years, mean (range)15.2 (4–47)
 Cobb ≥50° before 50 years old15
  Age at X-ray, years, mean (range)29.8 (8–49)
  Cobb angle, mean (SD)86.3 (27.0)
  • Cobb is Cobb angle of scoliosis.