Table 2

Descriptive analysis of the 46-SNP PRS

	n	sPRS
	n	Mean	SD	95% CI
Familial melanoma cases	418	0.80	1.14	0.69 to 0.91
No. of primary melanomas in case
One	338	0.71	1.11	0.59 to 0.83
Two or more	80	1.17	1.23	0.90 to 1.44
Family Clustering Score
Lowest 10%	39	0.94	1.26	0.55 to 1.33
Middle 10%–90%	288	0.85	1.16	0.72 to 0.98
Highest 10%	42	0.60	1.17	0.25 to 0.95
Population controls	3423	0	1	−0.03 to 0.03