Table 1

The Netchine-Harbison clinical scores of patients with SRS in this study

Clinical criteriaSRS-s01SRS-s03SRS-s04SRS-s09SRS-s11
SGA (birth weight and/or birth length)✓✓✓✓✓
Postnatal growth failure✓✓✓✓
Relative macrocephaly at birth✓✓✓✓
Protruding forehead✓✓✓✓
Body asymmetry✓✓✓
Feeding difficulties and/or low BMI✓✓✓ 
Age2 years3 years10 years2 years1 year
6 months
SexFemaleMaleMaleMaleFemale

  • A clinical diagnosis is considered if a patient has at least four of the six criteria.

  • BMI, body mass index; SGA, small for gestational age; SRS, Silver-Russell syndrome.