Table 3

Rates of pathogenic variants found in patients with DCIS

DCISTotal casesTotal PVs%BRCA1%BRCA2%TP53%BRCA1/BRCA2/
TP53 combined (%)
PALB2%
Total261142.327.727.7623.1038.513.8
≤25 years8337.500.0112.5225.0037.500.0
26–30 years18844.4211.115.6422.2038.915.6
Grade/type
 Unknown300.000.000.0000.000.0
  28225.000.0112.500%12.5112.5
  314857.1214.317.153657.100.0
 Pagets11100.000.000.01100100.000.0
 Comedo8450.000.000.045050.000.0
  • PV, pathogenic variant.