Table 1

Participant characteristics

IDStudy armAge (years)EthnicityMarital statusParityCarrier statusPersonal history of BCRRMNumber of relatives with OCNumber of relatives with BCAscertainmentPostcode
ID-01No surgery40CaucasianSingle0BRCA1NoYes01 SDRHigh-risk FCCLondon
ID-02RRSO41CaucasianMarried0BRCA2NoYes01 FDR, 1 SDRHigh-risk FCCEssex
ID-03RRESDO37CaucasianMarried3BRCA2NoNo1 SDR1 FDR, 1 SDRHigh-risk FCCEssex
ID-04RRSO46CaucasianMarried0BRCA1NoNo00High-risk FCCLondon
ID-05RRESDO43CaucasianSingle2BRCA1NoNo1 SDR3 SDRHigh-risk FCCLondon
ID-06RRESDO38CaucasianMarried2BRCA1NoYes03 SDRHigh-risk FCCSussex
ID-07No-surgery36AsianSingle1BRCA1NoNo1 SDR3 SDRHigh-risk FCCLondon
ID-08RRESDO46CaucasianMarried3BRCA2NoYes01 FDR, 1 SDRHigh-risk FCCCambridge
ID-09RRESDO39CaucasianMarried2BRCA1NoYes1 FDR, 1 SDR1 FDRHigh-risk FCCLondon
ID-10No-surgery39CaucasianMarried0BRCA1NoNo1 SDR1 FDRHigh-risk FCCLondon
ID-11RRESDO35CaucasianMarried2BRCA2NoNo1 FDR0High-risk FCCHertfordshire
ID-12No-surgery36CaucasianMarried1BRCA1NoNo2 SDR1 SDRHigh-risk FCCLondon
ID-13RRSO45CaucasianMarried1BRCA2NoYes00General gynaecology clinicDurham
ID-14No-surgery38CaucasianMarried1BRCA1Yes*No†00High-risk FCCLondon
ID-15RRESDO38CaucasianMarried2BRCA2NoNo00High-risk FCCHertfordshire
ID-16RRESDO44CaucasianMarried2BRCA2NoNo2 SDR1 SDRHigh-risk FCCHampshire
ID-17RRESDO39CaucasianMarried2BRCA1Yes‡No†00GO clinicNewport
ID-18RRESDO44CaucasianSingle2BRCA2NoYes01 FDR, 2 SDRHigh-risk FCCLondon
ID-19No surgery34CaucasianMarried2BRCA1NoNo01 SDRGenetics clinicSurrey
ID-20RRSO46AsianMarried2BRCA1NoNo1 FDR, 2 SDR2 SDRGO clinicAberdeen
ID-21RRESDO44CaucasianMarried2BRCA2Yes*Yes§1 FDR1 FDR, 1 SDRGO clinicDevon
ID-22RRSO39CaucasianMarried2BRCA2NoNo01 FDRGO clinicLiverpool
ID-23RRSO40CaucasianSingle2BRCA1NoNo1 FDR, 1SDR0High-risk FCCSurrey
ID-24RRSO40CaucasianMarried1BRCA1Yes‡Yes*§02 FDRGeneral gynaecology clinicCleveland
  • *Oestrogen receptor positive breast cancer.

  • †Bilateral therapeutic mastectomies.

  • ‡Triple negative breast cancer.

  • §Unilateral therapeutic mastectomy followed by contralateral risk reducing mastectomy.

  • BC, breast cancer; FCC, familial cancer clinic; FDR, first degree relative; GO, gynaecological oncology; OC, ovarian cancer; RRESDO, risk-reducing early salpingectomy with delayed oophorectomy; RRM, risk-reducing mastectomy; RRSO, risk-reducing salpingo-oophorectomy; SDR, second degree relative.