Table 1

Clinical characteristics of FIGC probands and their family history

IDSexAgeLaurenOtherRelatives with GC (age at diagnosis)Family history of other cancers (age at diagnosis)
At diagnosisHistologyPrimary tumour
P1M59IntestinalFDR (80)FDR unidentified (50); SDR unidentified (75)
P2M79IntestinalFDR (58)FDR prostate (79)
P3F81IntestinalFDR (63)FDR gastric ulcer (86)
P4M84IntestinalFDR (–)FDR unidentified (49)
P5M69IntestinalFDR (78)FDR gastric ulcer (80)
P6F80IntestinalFDR (47)FDR osteosarcoma (86); SDR colon cancer (67); FDR unidentified (45)
P7F62IntestinalFDR (63)FDR colorectal and breast (70); SDR thyroid (20)
P8M78IntestinalFDR (84); >TDR (60)FDR kidney (58); FDR lung (84)
P9F78IntestinalVaginaFDR (71)
P10F75IntestinalFDR (68, 50); SDR (80)FDR leukaemia (91); SDR unidentified (80)
P11M71IntestinalFDR (72)FDR lung (56); FDR unidentified (−)
P12M66IntestinalFDR (88); FDR GC and BC (45); SDR (80, 80, 70, 60, 44, 80); >TDR (79)SDR unidentified (80); TDR breast (24); TDR leukaemia (22); TDR prostate (60); TDR bladder (–); >TDR brain (40); TDR unidentified (40); >TDR prostate (73); >TDR gynaecological (–); >TDR osteosarcoma (65); >TDR breast (51)
P13M72IntestinalFDR (70)
P14F73IntestinalFDR (94); TDR (55)FDR hepatobiliary (75); FDR colorectal (70)
P15F75IntestinalFDR (49)FDR gastric ulcer (70); SDR gastric ulcer (21)
P17M83IntestinalFDR (74)FDR unidentified (55)
P18F66IntestinalFDR (47)FDR gastric ulcer (66); FDR breast (44)
P19M72IntestinalFDR (72, 70); SDR (76, 70)FDR laryngotracheal (71); FDR gastric ulcer (77)
P20M71IntestinalFDR (60)FDR breast (62); FDR lung (69)
P21M54IntestinalFDR (55); SDR (–)SDR osteosarcoma (84); FDR laryngotracheal (76)
P22M70IntestinalFDR (70)FDR lung (53)
P23F74IntestinalFDR (64); SDR (80)
P24M65IntestinalFDR (70)SDR oral cancer (75)
P25F88IntestinalFDR (80)FDR colon (85)
P26F54IntestinalFDR (97); SDR (90)
P27M64IntestinalFDR (66)FDR laryngotracheal (62, 58); SDR gastric ulcer (61, 68); SDR gynaecological (54); SDR hepatobiliary (70)
P28M73IntestinalFDR (80–70)SDR melanoma (37)
P29M70IntestinalFDR (68); SDR (60, 60)
P30F71IntestinalFDR (82)FDR colon (59); FDR unidentified (65, 72, 79); SDR leukaemia (70)
P32F80IntestinalFDR (50)FDR unidentified (50); SDR leukaemia (32); FDR liver (60); SDR liver (52)
P33M78IntestinalFDR (97)
P34M69IntestinalFDR (93)SDR leukaemia (70); FDR bladder (63)
P35M73IntestinalFDR (58, 75, 78)FDR lung (57)
P36M74IntestinalFDR (69, 60, 80, 60, 77); SDR (70)
P37F55IntestinalFDR (41, 58); SDR (65, 60)
P38F77IntestinalFDR (–); SDR (–)FDR lung (–)
P39M76IntestinalFDR (73)SDR breast (60)
P40M82IntestinalColonFDR (39)FDR breast (70)
P41M66IntestinalFDR (75)
P42F76IntestinalFDR (77, 92, 74)FDR brain (74)
P43M70IntestinalFDR (61); SDR (80)
P44F76IntestinalFDR (65)
P45M77IntestinalFDR (80)
P46M85IntestinalSDR (64)
P47M63IntestinalSDR (63)
P48M58IntestinalFDR (72–68)SDR liver (80)
P49F67IntestinalFDR GC and BC (90)FDR hepatobiliary (74); SDR melanoma (50)
P50M64IntestinalFDR (60–64)FDR laryngotracheal (66, –); SDR unidentified (–)
P51M70IntestinalColonFDR (76); SDR (60)FDR hepatobiliary (74); SDR unidentified (70); SDR colorectal (70)
P52M76IntestinalFDR (70)SDR colon (70)
  • (–), unknown; F, female; FDR, first-degree relative; FIGC, familial intestinal gastric cancer; GC, gastric cancer; GC and BC, gastric cancer and associated breast cancer; ID, identification; M, male; P, proband; SDR, second-degree relative; TDR, third-degree relative.