Table 1

Number of variants in the eQTL-attributed and GWAS-attributed lists

	eQTL-attributed variants	eQTL-attributed variants, confirmed by CoDeS3D	GWAS-attributed variants	GWAS-attributed variants, confirmed by CoDeS3D	Both analyses combined, Input	Both analyses, SNP-cohesin confirmed by CoDeS3D
Core cohesin genes
RAD21	14	11	2	1	16	12
RAD21-AS1	9	7	2	0	11	7
SMC1A	13	8	1	1	14	9
SMC3	9	4	2	0	11	4
STAG1	5	2	31	7	35	8
STAG2	9	2	0	0	9	2
Cohesin (Meiosis-only)
RAD21L1	2	2	2	1	4	3
REC8	15	6	1	0	16	6
SMC1B	9	7	4	2	13	9
STAG3	28	23	5	1	33	24
Subtotal	113	72	50	13	162	84
Cohesin-support
MAU2	19	11	17	13	35	23
NIPBL	5	0	7	0	12	0
PDS5A	13	7	6	2	19	9
PDS5B	14	6	19	8	32	13
WAPL	11	8	5	1	16	9
CTCF
CTCF	12	2	2	0	14	2
Subtotal	74	34	56	24	128	56
Total	187	106	106	37	290	140

The eQTL-attributed variant list consists of 187 variants, but after filtering results in 106 variants with significant spatial eQTLs. The GWAS-attributed variant list consists of 106 variants, but after filtering results in 37 variants with significant spatial eQTLs. Overall, the 290 attributed variants results in 140 variants with significant spatial eQTLs.
Red numbers indicate each one of the three overlapping SNPs (GWAS-attributed and eQTL-attributed).
eQTL, expression quantitative trail locus; GWAS, genome-wide association studies.