Table 1

Individuals carrying variants in autism-associated genes with comorbid intellectual disability (ID)

Autism-associated genesCases with IDAutism cases (with or without ID)Autism cases with comorbid IDAutism cases without ID
ADNP 134/134114/134114/1140/114
ANK2 1/11/11/10/1
ANKRD11 10/109/109/90/9
ARID1B 137/15380/15380/800/80
ASH1L 14/144/144/40/4
ASXL3 18/1916/1915/161/16
BCL11A 11/164/163/41/4
CHD2 3/33/33/30/3
CHD8 56/7561/7546/6115/61
CUL3 1/11/11/10/1
DDX3X 97/9733/9733/330/33
DYRK1A 7/269/267/92/9
KMT2A 76/9912/9910/122/12
MECP2 1/11/11/10/1
MYT1L 1/11/11/10/1
NRXN1 45/6034/6023/3411/34
POGZ 48/4929/4929/290/29
SCN2A 19/339/337/92/9
SETD5 15/167/167/70/7
SHANK3 35/3726/3724/262/26
SYNGAP1 11/2311/2311/110/11
TCF20 47/4832/4831/321/32
Total787/916 (85.9%)497/916 (54.3%)460/497 (92.6%)37/497 (7.4%)