Table 1

Demographic and clinical features of included patients and associations with diagnostic outcome

Characteristicsn (%)Genetically solved/unsolved cases
Sex
 Male48 (43)6/42
 Female64 (57)7/57
Median age at seizure onset, years (range)15 (1–67)9/15 (median)*
Seizure focus
 Temporal57 (51)4/53
 Frontal27 (24)5/22
 Parietal2 (2)0/2
 Occipital2 (2)2/0
 Unclassified24 (21)2/22
MRI
 Normal101 (90)12/89
 Hippocampal sclerosis/atrophy11 (10)1/10
Family history
 Positive (at least one first-degree or two second-degree relatives with seizures)37 (33)6/31
 Negative75 (67)7/68
History of FS
 Yes10 (9)1/9
 No102 (91)12/90
AED response
 Responsive6 (5)0/6
 Resistant86 (77)10/76
 Undefined20 (18)3/17
  • *Statistically significant, Mann-Whitney U-test: uncorrected p value=0.01.

  • AED, antiepileptic drug; FS, febrile seizure.