Table 2

Qualitative evaluation of ciliary beating: proportion per patient of ciliated edges with each beat pattern (as described by Chilvers et al,13 according to the ultrastructural phenotype)

2 DAODAIDA/MTDCCnEM
n=15n=15n=15n=15n=15
Normal beating0% (0–0)0% (0–59)0% (0–13)30% (0–62)35% (0–50)
Virtually immotile100% (100–100)88% (22–92)64% (6–93)13% (0–56)40% (5–85)
Stiff beating with reduced amplitude0% (0–0)10% (0–56)36% (7-81)45% (15-63)30% (0–56)
Circular gyrating motion0% (0–0)0% (0–0)0% (0–0) 5% (0–44) 0% (0–15)
  • Data are expressed as median (range). Grey boxes point out the specific beat pattern for each ultrastructural phenotype as published by Chilvers et al (nEM group was not evaluated by Chilvers).13

  • CC group, central complex defect; 2 DA group, combined outer/inner dynein arms defect.; IDA/MTD group, inner dynein arm defect with microtubular disorganisation; nEM group, normal ultrastructure; ODA group, outer dynein arm defect.