Volumes of eight subcortical brain regions (right and left hemisphere) in male and female deletion carriers and controls
| Hemisphere | Subcortical region | Volume in control female subjects (cm3) (n=415) | Volume in female deletion subjects (cm3) (n=14) | Statistical comparison Mann-Whitney U value, p value | Benjamini-Hochberg corrected p value |
| Left | Lateral ventricle | 7.62 (7.08 to 8.06) | 9.32 (7.50 to 11.18) | 2038, 0.059 | 0.189 |
| Thalamus | 7.15 (7.05 to 7.25) | 7.17 (6.19 to 7.53) | 2582.5, 0.480 | 0.640 | |
| Caudate | 3.20 (3.17 to 3.24) | 3.15 (2.91 to 3.21) | 2347, 0.226 | 0.452 | |
| Putamen | 4.84 (4.78 to 4.90) | 4.44 (3.82 to 4.99) | 1912, 0.030 | 0.120 | |
| Pallidum | 1.23 (1.19 to 1.25) | 1.15 (0.99 to 1.25) | 2168.5, 0.106 | 0.283 | |
| Hippocampus | 4.10 (4.05 to 4.15) | 4.08 (3.79 to 4.51) | 2823, 0.857 | 0.914 | |
| Amygdala | 1.48 (1.45 to 1.50) | 1.47 (1.30 to 1.57) | 2676.5, 0.617 | 0.705 | |
| Nucleus accumbens | 0.52 (0.50 to 0.53) | 0.44 (0.40 to 0.49) | 1668, 0.007 | 0.072 | |
| Right | Lateral ventricle | 7.17 (6.83 to 7.64) | 8.57 (7.48 to 10.58) | 2257, 0.159 | 0.363 |
| Thalamus | 6.28 (6.25 to 6.35) | 6.11 (5.83 to 6.70) | 2537, 0.420 | 0.611 | |
| Caudate | 3.30 (3.26 to 3.36) | 3.21 (3.04 to 3.44) | 2462, 0.338 | 0.541 | |
| Putamen | 4.64 (4.58 to 4.71) | 4.31 (3.88 to 4.63) | 1713, 0.009 | 0.072 | |
| Pallidum | 1.40 (1.39 to 1.42) | 1.31 (1.16 to 1.40) | 1816.5, 0.019 | 0.101 | |
| Hippocampus | 4.23 (4.20 to 4.27) | 4.19 (3.97 to 4.60) | 2903, 0.997 | 0.997 | |
| Amygdala | 1.53 (1.51 to 1.55) | 1.46 (1.37 to 1.76) | 2635, 0.554 | 0.682 | |
| Nucleus accumbens | 0.54 (0.53 to 0.55) | 0.50 (0.45 to 0.60) | 2460, 0.329 | 0.541 |
Data are presented as median values with 95% confidence limits.