Table 1

Demographic and clinical characteristics of study population

CharacteristicsCases (n=223)
Male gender, n (%)134 (60.1)
Birth weight, median (quartiles)2640 (1640–3200)
Gestational age*, median (quartiles)35 (31–39)
Age at diagnosis (days), median (quartiles)2 (0–18)
Age at death (days), median (quartiles)13 (3–42.5)
Proportion of caesarean section delivery (%)142/218 (65.1)
Proportion of abnormal MRI results (%)34/37 (91.9)
Proportion of abnormal EEG results (%)29/35 (82.9)
Ultrasonic cardiogram
 Normal (%)5/198 (2.5)
 PDA/PFO/ASD/PAH (%)132/198 (66.7)
 Arrhythmia3/198 (1.5)
 Complex malformation†41/198 (20.7)
 Cardiac insufficiency17/198 (8.6)
  • *Sixteen term infants missed the exact gestational age were not calculated.

  • †Complex malformation included pericardial effusion, ventricular septal defect, coarctation of the aorta and other functional defects.

  • ASD, atrial septal defect; PAH, pulmonary artery hypertension; PDA, patent ductus arteriosus; PFO, patent foramen ovale.