Sociodemographic characteristics of cohorts
| Carriers (n=44) | Controls (n=44) | ||
| Sex | χ2=0.00, p=1.00 | ||
| Female | 27 (61%) | 27 (61%) | |
| Male | 17 (39%) | 17 (39%) | |
| Age | t=−0.33, p=0.75 | ||
| Mean | 37.6 | 38.3 | |
| Range | 19–58 | 22–59 | |
| Ethnicity | χ2=1.38, p=0.71 | ||
| White | 42 (95%) | 40 (91%) | |
| Asian/Asian British | 1 (2%) | 2 (5%) | |
| Chinese/Other | 0 | 1 (2%) | |
| Mixed | 1 (2%) | 1 (2%) | |
| Education | χ2=21.39, p=<0.005* | ||
| None | 2 (5%) | 0 | |
| School to 16 | 9 (20%) | 3 (7%) | |
| School to 18 | 9 (20%) | 1 (2%) | |
| Technical | 10 (23%) | 5 (11%) | |
| Degree/postgraduate | 14 (32%)* | 34 (77%)* | |
| Missing | 0 | 1 (2%) | |
| Employment | χ2=2.05, p=0.56 | ||
| Currently employed | 36 (82%) | 38 (86%) | |
| Not currently employed | 6 (14%) | 3 (7%) | |
| Retired | 2 (5%) | 2 (5%) | |
| Missing | 0 | 1 (2%) | |
| Marital status | χ2=0.72, p=0.70 | ||
| Married | 15 (63%) | 29 (66%) | |
| Single | 9 (38%) | 14 (32%) | |
| Divorced | 0 | 1 (2%) | |
| Missing | 20 | 0 | |
| Socioeconomic classification | χ2=11.22, p=0.04* | ||
| Professional/managerial | 21 (48%)* | 36 (82%)* | |
| Skilled manual/non-manual | 15 (34%) | 5 (11%) | |
| Partly skilled manual/unskilled | 8 (18%) | 3 (7%) | |
| Missing | 0 | 0 | |
*Significant difference between carriers and controls.