Table 1

Characteristics of all included individuals

ORIGO cohortFamily-based cohort
CasesControlsCasesUnaffected relatives
Number 357327323262
Age
 Mean (SD)56 (10)46 (14)51 (11)62 (17)
 Range23–8418–9026–9017–94
Country of origin
 The Netherlands357327317249
 Hungary614
First breast tumour
 Invasive (%)313 (88)317 (98)
 DCIS (%)32 (9)4 (1)
 Unknown (%)12 (3)2 (1)
Second breast tumour
 Invasive (%)19 (5)51 (16)
 DCIS (%)2 (1)4 (1)
 Unknown (%)0 (0)5 (2)
Family score
 BOADICEAFH (SD)1.03 (0.40)1.05 (0.39)
 BOADICEALTR (SD)0.23 (0.07)0.23 (0.06)
  • BOADICEAFH, Breast cancer family history score; BOADICEALTR, Breast cancer lifetime risk at age 80; DCIS, ductal carcinoma in situ.