Molecular signatures at junction sequences
Molecular signatures | Junctions | Total 216 | ||
Simple (n=68) | CCR (n=44) | Chromoanagenesis (n=104) | ||
Deletion (1–26 355 bp) | 48 | 30 | 52 | 130 (60.1%) |
1–10 bp | 33 | 14 | 28 | 75 |
11–1000 bp | 10 | 12 | 18 | 40 |
>1000 bp | 5 | 4 | 6 | 15 |
Gain (1–71 339 bp) | 14 | 7 | 33 | 54 (25%) |
1–10 bp | 13 | 7 | 32 | 52 |
11–1000 bp | 0 | 0 | 1 | 1 |
>1000 bp | 1 | 0 | 0 | 1 |
Insertion (1–72 bp) | 14 | 12 | 18 | 44 (20.3%) |
Templated | 11 | 5 | 111 | 27 |
Random | 3 | 7 | 7 | 17 |
Microhomology | ||||
0–1 bp | 33 | 28 | 64 | 125 |
2–4 bp | 27 | 15 | 32 | 74 |
≥5 bp | 8 | 1 | 8 | 17 |
CCR, complex chromosomal rearrangements.