Genomic features disrupted by chromosomal breakpoints
| Disrupted elements | Breakpoints | Total 218 | ||
| Simple (n=68) | CCR (n=45) | Chromoanagenesis (n=105) | ||
| Gene | 34 | 21 | 40 | 95 (43.5%) |
| TAD | 60 | 39 | 93 | 192 (88%) |
| Repeated elements | 30 | 26 | 54 | 110 (50.4%) |
| SINE | 7 | 7 | 13 | 27 |
| LINE | 11 | 12 | 20 | 43 |
| LTR | 4 | 6 | 14 | 24 |
| DNA | 5 | 1 | 4 | 10 |
| Satellite | 1 | 0 | 1 | 2 |
| Segmental duplication | 2 | 0 | 2 | 4 |
Repeated elements were defined according to Repeat Masker. TAD were defined according to GM12878 map.25
CCR, complex chromosomal rearrangements; TAD, topologically associated domain.