Prevalence of pathogenic germline BRCA1/2 variants according to age at diagnosis
| Age (years) | Tested | BRCA1 | BRCA2 | Combined BRCA1/2 |
| <30 | 6 | 0 | 0 | 0 (0) |
| 30–39 | 20 | 4 | 1 | 5 (25) |
| 40–49 | 113 | 22 | 5 | 27 (24) |
| 50–59 | 213 | 30 | 12 | 42 (20) |
| 60–69 | 140* | 9 | 12 | 21 (15) |
| ≥70 | 65† | 3 | 5 | 8 (12) |
Data are reported as number (percentage; the denominator is column 2 ‘Tested’).
*84/140 (60%) had a family history of breast or ovarian cancer and 37/140 (26%) had a medical history of breast cancer.
†45/65 (69%) had a family history of breast or ovarian cancer and 22/65 (34%) had a medical history of breast cancer.