Association between polygenic risk scores (PRS) and ovarian cancer in different age groups
| Age group | Overall | Serous | ||
| OR (95% CI) | P values | OR (95% CI) | P values | |
| All ages | 1.32 (1.21 to 1.45) | 5.38×10–10 | 1.43 (1.29 to 1.58) | 1.28×10–11 |
| <60 | 1.29 (0.91 to 1.86) | 0.16 | 1.46 (1.01 to 2.17) | 0.05 |
| 60–69 | 1.28 (1.11 to 1.49) | 8.99×10–4 | 1.34 (1.14 to 1.59) | 4.51×10–4 |
| ≥70 | 1.36 (1.20 to 1.55) | 3.02×10–6 | 1.47 (1.26 to 1.72) | 7.10×10–7 |
| Interaction | 1.00 (0.99 to 1.02) | 0.88 | 1.00 (0.98 to 1.02) | 0.95 |
In the overall PRS analysis, we used cases of any type of ovarian cancers and in the serous PRS analysis we used cases of serous ovarian cancer.