Univariate and multivariate analyses for risk factors of central nervous system haemangioblastoma-specific survival
| Variables | Univariate analysis | Multivariate analysis | ||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Onset age (≤30 vs >30 years) | 4.434 (2.358 to 8.338) | <0.001 | 2.818 (1.402 to 5.662) | 0.004 |
| Sex (male vs female) | 1.213 (0.674 to 2.185) | 0.520 | 1.323 (0.722 to 2.426) | 0.365 |
| Birth year | 1.005 (0.979 to 1.031) | 0.725 | 0.982 (0.954 to 1.011) | 0.229 |
| Birth order (first vs others) | 0.825 (0.432 to 1.577) | 0.561 | 0.789 (0.411 to 1.517) | 0.478 |
| Family history (yes vs no) | 2.066 (0.912 to 4.684) | 0.082 | 2.551 (1.084 to 6.000) | 0.032 |
| Mutation (missense vs truncating) | 0.653 (0.358 to 1.190) | 0.164 | 0.711 (0.383 to 1.320) | 0.280 |
| First symptom (haemangioblastoma vs abdomen) | 12.52 (3.030 to 51.69) | <0.001 | 8.840 (2.037 to 38.37) | 0.004 |