Table 1

Agreed panels

Breast cancerOvarian cancerColorectal cancer/polyposis
ATM*
BRCA1
BRCA2
CHEK2†
PALB2
PTEN
STK11
TP53		BRCA1
BRCA2
BRIP1
MLH1
MSH2
MSH6
RAD51C
RAD51D		APC
BMPR1A
EPCAM (del exons 8–9)
GREM1 (upstream dup)‡
MLH1
MSH2
MSH6
MUTYH
NTHL1‡
PMS2
POLE
POLD1
PTEN
SMAD4
STK11

  • *Truncating variants plus ATM c.7271T>G, p.(Val2424Gly).

  • †Truncating variants.

  • ‡Optional.