Table 1

Associations* observed in regions previously reported to affect telomere length(TL) based on a genome-wide association analysis of 6.3 million SNPs (n=5075)

SNP identifierChrGeneMajor alleleMinor alleleMAFβ†SEP
rs126388623 TERC AG0.24−×10–8
rs77055265 TERT CA0.430.090.026.4×10–6
rs229743920 RTEL1 TG0.25−×10–7
  • *Association estimates are adjusted for sex, age, TL measurement type and measurement batch.

  • †Association estimates are for the minor allele. The major allele is the reference allele.

  • MAF, minor allele frequency.