Table 3

Adjusted predicted margins and multiple pairwise comparisons

Variant status of participantsSample sizeMargin (QTc)Delta-method
SE
Unadjusted groupsBonferroni groups
(A) Men†
 Negative for all variants91426.42.6AA
 L353L15440.44.9BAB
 V205M21455.84.1CB
 V205M*L353L5504.49.1DC
(B) Women‡
 Negative for all variants169448.41.9AA
 K897T18444.05.7AA
 L353L40458.14.9ABAB
 L353L*K897T3483.210.0CB
 V205M40479.25.1CB
 V205M*K897T3447.52.6AA
 V205M*L353L7474.512.2BCAB
 V205M*L353L*K897T2459.04.0BAB
(C) Men and women combined‡
 Negative for all variants260441.21.5AA
 K897T23440.45.4ABAB
 L353L55452.13.7BCAB
 L353L*K897T3470.411.0CDABC
 V205M61470.53.6DC
 V205M*K897T3443.12.9ABAB
 V205M*L353L12488.811.0DC
 V205M*L353L*K897T2455.03.8CBC
  • Margins sharing a letter in the group label are not significantly different at the 5% level.

  • *Adjusted for six comparisons' should be preceded by only 1 symbol (as seen above for men)

  • †Adjusted for six comparisons.

  • ‡Adjusted for 28 comparisons.

  • QTc, corrected QT.