Tonsillectomy GWAS | GWAS catalogue associations | ||||||||
---|---|---|---|---|---|---|---|---|---|
Position (bp) SNP (effect/alternative allele) | p Value | OR (95% CI) | r2 | Disease | Risk allele | Risk allele freq | p Value | OR (95% CI) | PMID |
30 494 371 rs2412971 (G/A) | 6.99E-9 | 1.27 (1.17 to 1.37) | 1 | IgA nephropathy | G | 0.49 | 1.86E-9 | 1.25 (NA) | 21399633 |
6.99E-9 | 1.27 (1.17 to 1.37) | 1 | IgA nephropathy | G | 0.54 | 4.80E-12 | 1.20 (NA) | 25305756 | |
6.99E-9 | 1.27 (1.17 to 1.37) | 1 | IgA nephropathy | G | 0.67 | 6.00E-11 | 1.35 (NA) | 25305756 | |
30 486 826 rs2412970 (A/G) | 1.64E-8 | 1.26 (1.16 to 1.37) | 0.997 | Inflammatory bowel disease | G | 0.46 | 2.70E-14 | 1.08 (1.05 to 1.11) | 23128233 |
1.64E-8 | 1.26 (1.16 to 1.37) | 0.997 | Optic disc area | G | 0.43 | 3.40E-8 | 1.02 (NA) | 25631615 | |
30 529 631 rs2412973 (C/A) | 1.92E-8 | 1.26 (1.16 to 1.37) | 0.987 | IgA nephropathy | C | 0.49 | 4.46E-9 | 1.25 (NA) | 21399633 |
1.92E-8 | 1.26 (1.16 to 1.37) | 0.987 | Inflammatory bowel disease (early onset) | A | 0.46 | 1.55E-9 | 1.15 (1.01 to 1.31) | 19915574 | |
30 592 487 rs713875 (G/C) | 3.25E-8 | 1.26 (1.16 to 1.36) | 0.988 | Crohn’s disease | C | 0.47 | 7.30E-12 | 1.08 (1.04 to 1.13) | 21102463 |
30 423 460 rs12537 (C/T) | 9.33E-6 | 1.21 (1.11 to 1.32) | 0.791 | IgA nephropathy | C | 0.81 | 1.17E-11 | 1.28 (1.19 to 1.39) | 22197929 |
30 337 586 rs36600 (C/T) | 5.69E-5 | 1.21 (1.10 to 1.33) | 0.625 | Lung cancer | A | 0.09 | 6.20E-13 | 1.29 (1.20 to 1.38) | 21725308 |
bp, base pair; GWAS, genome-wide association study; PMID, PubMed ID number for the article reporting the association; r2, correlation with rs2412971.