Spontaneous and DEB-induced chromosome breaks in 900677A and other lines
| Sample | Dose (mg/mL) | Mean breaks/cell |
|---|---|---|
| GM16631 (FANCA−/−) | 0 | 0.18 |
| 0.01 | 1.52 | |
| GM16754 (FANCC−/−) | 0 | 0.10 |
| 0.01 | 1.44 | |
| 900677A (XRCC2−/−) | 0 | 0.22 |
| 0.01 | 0.48 | |
| 0.1 | 2.35 | |
| NL143889 (normal fibr.) | 0 | 0.00 |
| 0.01 | 0.04 | |
| 0.1 | 0.15 |
DEB, diepoxybutane.