Table 1

Distribution of cases and controls by age, race/ethnicity and study centre

	Case–control mutation screening for rare variants in nine moderate-risk genes				Case–control SNP genotyping for 18 BCAC SNPs
Distributions	Case	%	Control	%	Case	%	Control	%
Age range, years
≤30	106	8.2	67	6.0	97	7.8	61	5.8
31–35	319	24.6	171	15.3	300	24.3	157	14.9
36–10	433	33.4	238	21.2	409	33.1	220	20.8
41–45	439	33.9	203	18.1	430	34.8	183	17.3
46–50	0	0	230	20.5	0	0	225	21.3
51–55	0	0	212	18.9	0	0	211	20.0
Race/ethnicity
Caucasian	840	64.8	967	86.3	788	63.8	904	85.5
East Asian	202	15.6	71	6.3	193	15.6	70	6.6
Latina	158	12.2	47	4.2	158	12.8	47	4.5
Recent African Ancestry	97	7.5	36	3.2	97	7.9	36	3.4
Study centre
BCFR-Australia	588	45.4	522	46.6	551	44.6	472	44.7
BCFR-Canada	299	23.1	463	41.3	284	23.0	499	42.5
BCFR-Northern California	410	31.6	136	12.1	401	32.4	136	12.9
Total	1297		1121		1236		1057

Subjects were excluded from mutation-screening if performance was poor; percentage data are the total number of cases on control DNA in the category indicated that met the mutation-screening quality control standards.
BCAC, Breast Cancer Association Consortium; BCFR, Breast Cancer Family Registry.