Table 2

Age at diagnosis and pathology characteristics of BRCA1/BRCA2 mutation carriers

BRCA1/2+ (n=18)BRCA1/2 VUS (n=15)Non-BRCA1/2 (n=199)
Age (years), mean (range)49.5 (40–75)64.8 (41–84)66.1 (28–89)
BRCA1, n (%)12 (67)3 (20)N/A
BRCA2, n (%)6 (33)12 (80)N/A
Pathology, n
 High-grade serous1511166
 Endometrioid1415
 Adenocarcinoma2013
 Mixed types005
Stage, n
 I4525
 II006
 III129112
 IV2139
 Not classified0015
  • VUS, variants of unknown significance.