Table 1

Clinical summary

Patient	Age at pathological diagnosis	Disease
Patient 1	In utero*	Bilateral lung cysts
	Birth*; 5 days	Bilateral CCAM, revised later to type I PPB†
	Birth*	Scrotal web and testicular cyst
	9 months*; 1.7 years	Multiple small bowel polyps: enteritis cystica profunda†
	25 months	Type II PPB†
	25 months	PPB brain metastasis #1†
	3.1 years	PPB brain metastasis #2†
	8 years	NCMH
	10.5 years	PPB brain metastasis #3†
	10.9 years	PPB brain metastasis #4†
Patient 2	13 months*; 1.2 years	Hamartomatous bilateral renal cysts, NOS†
	13 months*; 2.5 years	Benign multifocal bilateral lung cysts, NOS†
	Birth*; 2 years	L ocular ‘pre-phthisical changes’: vascular mass and recurrent retinal detachments
	7.7 years	Pineoblastoma†
	10.6 years	Follicular variant of papillary thyroid carcinoma†
	13.4 years	L ovarian SLCT†
	15.1 years	Unusual hamartomatous nasal polyp, not otherwise categorised†
	15.7 years	R ovarian SLCT†
	17.2 years	R teratoid CBME†
Patient 3	10 days	R CCAM†, revised to type I PPB†; L lung cysts
	6 months	Hamartomatous juvenile intestinal polyps†
	1 month	R renal medullary malformation with disorganised collecting system and dilated lymphatic vessels†
	1.1 years	L CN†
	6.8 years	NCMH
Patient 4	11 months*	Bilateral multifocal lung cysts; L CCAM†; revised to type I PPB†
	1.7 years	R infected pulmonary cyst†
	4.1 years	L residual type I PPB with polypoid type II PPB†

*Age at detection.
†Pathological diagnosis.
CBME, ciliary body medulloepithelioma; CCAM, congenital cystic adenomatoid malformation; CN, cystic nephroma; L, left; NCMH, nasal chondromesenchymal hamartoma; NOS, not otherwise specified; PPB, pleuropulmonary blastoma; R, right; SLCT, Sertoli–Leydig cell tumour.