Linkage disequilibrium between READ1 alleles and KIAHap in the CLDRC cohort
| READ1 Allele | Cis with KIAHap | Trans with KIAHap | Freq. Cis | Freq. Trans |
|---|---|---|---|---|
| 1 | 199 | 403 | 0.3306 | 0.6694 |
| 3 | 33 | 51 | 0.3929 | 0.6071 |
| 4 | 33 | 91 | 0.2661 | 0.7339 |
| 5 | 1 | 30 | 0.0323 | 0.9677 |
| 6 | 10 | 29 | 0.2564 | 0.7436 |
| 10 | 7 | 43 | 0.1400 | 0.8600 |
| Del | 44 | 64 | 0.4074 | 0.5926 |
Transmission data for 132 informative CLDRC families (KIAHap present in at least one parent) is shown. The table shows the number of instances of each common READ1 allele (and the microdeletion) that occurred on the same chromosome as KIAHap (cis) versus on the other chromosome (trans), in all individuals carrying both that allele and KIAHap. Frequencies of cis and trans are also shown. Cis/trans status was elucidated by pattern of transmission in each family.
CLDRC, Colorado Learning Disabilities Research Center.