Table 4

Putatively functional SNPs correlated with rs3024493

SNPPositionr2 with rs3024493Variant LocationH3K27Ac markDNaseI siteTranscription factor binding site
rs3024505chr1:2069399040.947Intergenic (1 kb downstream of IL10)YesYesNFKB, STAT3, PU.1
rs3024495chr1:2069424130.947IL10 intronicYes
rs3024493chr1:206943968IL10 intronicYesYesNFKB, STAT3, POL2
rs3122605chr1:2069550410.853Intergenic (9.2 kb upstream of IL10)YesBATF
rs61815643chr1:2069561160.732Intergenic (10 kb upstream of IL10)YesYesNFKB
  • rs3024493 was queried against 1000 genome project (1KGP) database for most correlated proxies (r2>0.7). The correlated SNPs were tested and annotated by functional impact using ANNOVAR40 and ENCODE database for multiple functional tracks. The table only lists the tracks with mapping location of correlated variants.

  • SNP, single nucleotide polymorphism.