Table 4

Poisson regression analysis of eGFR slope at −2.0 mL/min/1.73 m2/year for 18 participants who met the UCPR goal

VariableRelative risk95% CIp Value
Age: ERT started (years)1.0721.008 to 1.1390.026
Interval: ERT start to visit 0 (years)0.8810.771 to 1.0060.062
Average systolic blood pressure (mm Hg)1.0110.991 to 1.0330.287
Average UPCR during treatment (mg/g)1.4790.630 to 3.4680.369
Male gender1.1300.637 to 2.0050.675
Medication score1.3920.859 to 2.2540.179
  • Relative risk presented as ratios (95% CI). Medication score defined as: 0, none; 1, ACE inhibitor or ARB; 2, ACE inhibitor plus ARB, or diuretic; 3, ACE inhibitor or ARB at maximum dose. p<0.05 for risk ratios from Poisson regression model (shown in bold).

  • ARB, angiotensin type 1 receptor blocker; eGFR, estimated glomerular filtration rate; ERT, enzyme replacement therapy; UPCR, urinary protein to creatinine ratio (g/g).