Age | Outcome | N | Coefficient* | 95% CI | p Value |
---|---|---|---|---|---|
Cross-sectional analysis | |||||
Birth | zBW | 1237 | 0.008 | −0.011 to 0.026 | 0.422 |
2 years† | zWT | 1820 | 0.012 | −0.003 to 0.027 | 0.134 |
2 years† | zHT | 1820 | 0.009 | −0.006 to 0.025 | 0.246 |
≤20 years | zWT-HT | 2211 | 0.008 | −0.002 to 0.017 | 0.108 |
Adults‡ | zWT | 1426 | 0.018 | 0.001 to 0.035 | 0.034 |
Adults‡ | zHT | 1426 | 0.004 | −0.012 to 0.021 | 0.609 |
>20 years | zWT-HT | 1426 | 0.025 | 0.007 to 0.044 | 0.006 |
Adults‡ | zBMI | 1426 | 0.016 | −0.001 to0.034 | 0.060 |
Longitudinal analysis | |||||
0–2 years | WT growth | 1248 | 0.001 | −0.009 to 0.012 | 0.810 |
0–2 years | LG growth | 1214 | 0.005 | −0.000 to 0.011 | 0.064 |
2–20 years | zWT change | 872 | 0.010 | −0.016 to 0.035 | 0.455 |
2–20 years | zHT change | 872 | 0.006 | −0.020 to 0.032 | 0.666 |
*Coefficients indicate change in z-scores per allele (cross-sectional) or change in z-scores per allele per year (longitudinal).
†Nearest observation to 2 years of age (>1.5 and <2.5 years).
‡First measurement at adult age (>20 years).
BMI, body mass index; BW, birthweight; HT, height; LG, length; WT, weight; zBMI, BMI z-score; zBW, BW z-score; zHT, height-for-age z-score; zWT, weight-for-age z-score; zWT-HT, weight-for-height z-score.
Results significant at the p<0.05 level are indicated in bold.