SNPs† | Haplotype | Control Neg | Control Pos | Case Neg | Case Pos | OR | p Value‡ |
---|---|---|---|---|---|---|---|

Multiple SNPs | |||||||

rs3116605_G | 1010 | 18 718 | 26 | 11 059 | 161 | 10.5 | 3×10^{−43} |

rs17074558_A | |||||||

rs279072_G | |||||||

rs1928123_C | |||||||

Split A | 1010 | 9558 | 12 | 5522 | 77 | 10.9 | 9×10^{−22} |

Split B | 1010 | 9360 | 14 | 5537 | 84 | 10.1 | 5×10^{−23} |

*In all cases the model was: one copy of the haplotype vs zero copies of the haplotype.

†Letters designate the minor allele nucleotide at the SNP location in the control population. If the haplotype has a one at a particular location, this indicates that this haplotype is has the minor SNP allele at this location; zero indicates the opposite.

‡The p values presented have not been corrected for the total number of SNP-haplotypes or single-SNPs tested. The total number of SNP-haplotypes (of any length from 1 to 15 SNPs) was 26 180. Therefore, the Bonferroni-corrected p value for the multi-SNP-haplotype is 1×10

^{−38}, which is still well below the uncorrected p value for the single-SNP.SNP, single nucleotide polymorphism.