Deafness in aminoglycoside users compared with all hearing study participants
| All | Asian | European | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Variant | N | OR | OR p value | N | OR | OR p value | N | OR | OR p value |
| MT-RNR1 m.839A>G | 1964 | 2.62 (0.83 to 4.42) | 0.004 | 1964 | 2.62 (0.83 to 4.42) | 0.004 | |||
| MT-RNR1 m.1095T>C | 990 | 2.03 (0.74 to 3.31) | 0.002 | 990 | 2.03 (0.74 to 3.31) | 0.002 | |||
| MT-RNR1 m.1107T>C | 475 | 1.4 (0.21 to 2.58) | 0.021 | 475 | 1.4 (0.21 to 2.58) | 0.021 | |||
| MT-RNR1 m.1494C>T | 2254 | 2.47 (1.04 to 3.91) | 0.001 | 1964 | 2.8 (1.05 to 4.56) | 0.002 | |||
| MT-RNR1 m.1555A>G | 3842 | 3.5 (2.53 to 4.46) | 0.000 | 3024 | 4.06 (3.03 to 5.09) | 0.000 | 455 | 3.14 (0.81 to 5.48) | 0.008 |