Microsatellite and single-nucleotide polymorphism (SNP) markers in ∼0.5 Mb region surrounding TCF20 to distinguish c.4670C>T haplotypes in families 3, 4 and 5
| Tcms4* 42390888 bp | Tcfms3 42433133 bp | Tcfms2 42433855 bp | Tcfms1 42544517 bp | rs2899354 42554409 bp | rs4453786 42563308 bp | rs16986035 42602139 bp | c.4670C>T 42606642 bp | rs5758652 42612408 bp | rs1548304 42691488 bp | rs6002674 42694220 bp | rs11704558 42695148 bp | rs6002676 42697216 bp | Tcfms5 42775494 bp | Tcfms6 42782403 bp | Tcfms7 42939056 bp | Tcfms8 43053571 bp | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Family 3 (father) | 158/162 | 200/202 | 203/203 | 200/214 | C/A | A/G | A/A | C/C | A/G | C/T | C/T | C/C | G/A | 182/184 | 164/166 | 202/202 | 219/223 |
| Family 3 (mother) | 156/156 | 206/206 | 205/205 | 204/206 | C/C | G/G | G/G | C/T | A/A | C/C | T/T | C/T | G/A | 184/184 | 166/166 | 202/206 | 213/223 |
| Family 3 (proband) | 156/162 | 202/206 | 203/205 | 200/206 | C/C | G/G | G/A | C/T | A/A | C/C | T/T | C/C | A/A | 182/184 | 164/166 | 202/206 | 213/223 |
| Family 3 c.4670T haplotype† | 156 | 206 | 205 | 206 | C | G | G | T | A | C | T | C | A | 184 | 166 | 206 | 213 |
| Family 4 (father) | 156/162 | 200/206 | 201/205 | 204/214 | C/A | A/G | G/A | C/T | A/G | C/T | T/T | C/C | A/A | 184/186 | 166/166 | 202/202 | 219/225 |
| Family 4 (mother) | 156/162 | 200/206 | 203/205 | 200/204 | C/C | G/G | A/G | C/C | A/A | C/C | T/T | T/T | G/G | 188/188 | 164/166 | 202/202 | 219/221 |
| Family 4 (proband) | 162/162 | 200/206 | 203/205 | 200/204 | C/C | G/G | G/G | C/T | A/A | C/C | T/T | C/T | G/A | 186/188 | 166/166 | 202/202 | 219/221 |
| Family 4 c.4670T haplotype | 162 | 200/206 | 205 | 204 | C | G | G | T | A | C | T | C | A | 186 | 166 | 202 | 219 |
| Family 5 (mother) | 162/162 | 200/202 | 201/205 | 200/200 | C/C | G/G | G/G | C/C | A/A | T/C | C/T | C/T | G/G | 184/186 | 166/170 | 202/202 | 219/223 |
| Family 5 (father) | 156/162 | 200/206 | 203/205 | 200/204 | C/A | G/A | A/G | C/T | A/G | T/T | T/T | C/C | G/A | 186/186 | 166/168 | 202/202 | 219/221 |
| Family 5 (proband) | 162/162 | 200/206 | 203/205 | 200/204 | C/C | G/G | A/G | C/T | A/A | T/C | T/T | C/T | G/A | 186/186 | 166/170 | 202/202 | 219/219 |
| Family 5 c.4670T haplotype | 162 | 206 | 203 | 204 | C | G | A | T | A | T | T | C | A | 186 | 166 | 202 | 219 |
*See online supplementary table S2 for details of markers.
†The haplotype associated with the c.4670C>T change in each family is shown in bold, markers in each pedigree that differ from those in the other two pedigrees are underlined.