Table 7

Pros and cons of participating in a surveillance programme

ProsCons
1. Possible early detection of BTs, allowing complete resection
2. Early detection of adenomas in the small bowel and colorectum before malignant degeneration
3. Early detection of BTs, which allows the most effective surgery and chemotherapeutic regimen to be determined4. Early detection of NHL and leukaemia, which allows the most effective chemotherapeutic regimen to be determined
1. Brain MRI may reveal small lesions of unknown significance. The only management is follow-up MRI at a short interval, which may increase anxiety
2. Claustrophobia (MRI) in adults
3. Video capsule endoscopy: risk of retaining capsule
4. Colonoscopy: risk of perforation (1/1000) and risk of bleeding after polypectomy (3–4%)
5. Greater awareness of being at high risk for developing cancers
6. Increased psychological distress before and after surveillance examination
7. Uncertainty about effectiveness of prevention programme and early treatment8. Complications of general anaesthesia
  • BT, brain tumour; NHL, non-Hodgkin lymphoma.