TableĀ 1

BRAF c.1799T>A p.Val600Glu mutation and MLH1 promoter region methylation in MLH1 mutation carriers and sporadic MLH1 loss cancers

Tumour statusMutant BRAF AND MLH1 methylationwt BRAF AND normal MLH1Mutant BRAF AND normal MLH1wt BRAF AND MLH1 methylation
MLH1 mutation carriers tumours n=71 (%)066 (92.9)1 (1.4)4 (5.6)
MMR-deficient sporadic tumours n=73 (%)46 (63.0)7 (9.6)2 (2.7)18 (24.7)
  • MMR, mismatch repair.