Parameter | Patients (n=12) | Predicted (LLN)† (n=12) | % of predicted | Paired t test | Controls (n=3) | Predicted (LLN)† (n=3) | % of predicted | Paired t test |
IVC | 3.94±0.97 | 4.50 (3.60)±0.84 (0.68) | 82%±14% | 0.0038* | 4.56±0.74 | 4.69 (3.86)±1.16 (0.96) | 99%±9% | 0.71 |
FEV1 | 2.56±0.70 | 3.63 (2.87)±0.60 (0.50) | 68%±11% | 7.88×10-8* | 3.76±0.74 | 3.85 (3.76)±0.87 (0.74) | 98%±4% | 0.41 |
FEV1/IVC | 0.65±0.06 | 0.82 (0.71)±0.06 (0.06) | 80%±7% | 1.86×10−6* | 0.82±0.06 | 0.83 (0.82)±0.02 (0.06) | 99%±9% | 0.84 |
TLC | 6.01±1.43 | 6.46 (5.39)±1.11 (0.92) | 93%±14% | 0.12 | 6.36±1.47 | 6.19 (5.19)±1.39 (1.17) | 103%±5% | 0.42 |
* Denote significant difference of p<0.05 using two-tailed paired t test.
† Predicted reference values and lower limit of normal (LLN) according to Stanojevic et al (2008) or Roberts et al (1991).36
Plus–minus values are means±SD.
BMI, body mass index; IVC, inspiratory vital capacity; FEV1, forced expiratory volume in 1 s; TLC, total lung capacity.