Cumulative cancer risk* by age and type of cancer in 146 patients with PTEN hamartoma tumour syndrome
| Sites | 20 years | 30 years | 40 years | 50 years | 60 years | 70 years |
|---|---|---|---|---|---|---|
| All cancers | 8% (4% to 14%)† | 23% (16% to 32%) | 40% (32% to 52%) | 65% (54% to 77%) | 75% (62% to 87%) | 85% (70% to 95%) |
| Breast (female) | 0 | 8% (3% to 20%) | 27% (16% to 44%) | 77% (59% to 91%) | 77% (59% to 91%) | 77% (59% to 91%) |
| Thyroid | 5% (2% to 11%) | 11% (7% to 19%) | 20% (13% to 30%) | 30% (20% to 44%) | 38% (25% to 56%) | 38% (25% to 56%) |
*Cumulative risks were estimated using Kaplan–Meier method and Stata software.
†95% CIs in parentheses.