Premalignancies and non-malignant tumours in 146 CMMRD patients
| Type of neoplasia | Number of patients | Median age at first diagnosis in years | Age range at first diagnosis in years |
|---|---|---|---|
| Adenomas/polyps of colon and rectum | 52 | 14 | 6–46 |
| Duodenal adenomas/polyps | 8 | 14 | 10–32 |
| Gastric polyps | 1 | n.r. | n.r. |
| Hepatic adenomas | 3 | 9 | – |
| Neurofibromas | 7 | n.r. | n.r. |
| Optic glioma | 1 | 3 | |
| Pilomatricomas (epithelioma of Malherbe) | 2 | 2 years 8 months | – |
| Polyps of vocal cord | 1 | in infancy | – |
CMMRD, constitutional mismatch repair deficiency; n.r., not reported.