Summary of 146 CMMR-patients from 91 families
| Gene | Number of patients (families) | Mean age at first malignancy (years) | Age range at first malignancy (years) | Per cent of patients with second metachronous malignancy |
|---|---|---|---|---|
| MLH1/MSH2 | 32 (19) | 7.5 | 0.4–39 | 22 |
| MSH6 | 29 (17) | 8 | 2–31 | 34 |
| PMS2 | 85 (55) | 10 | 1–28 | 42 |