Regression analyses of the 16 Tag SNPs
| SNP | A1 | *Add locus to rs6581155 | †Add rs6581155 to locus | ||
|---|---|---|---|---|---|
| p | OR (95% CI) | p | OR (95% CI) | ||
| rs1678542 | C | 0.2223 | 0.94 (0.86 to 1.04) | 0.0001393 | 0.82 (0.74 to 0.91) |
| rs2888334 | C | 0.8487 | 0.99 (0.89 to 1.1) | 0.0001001 | 0.8 (0.72 to 0.9) |
| rs775249 | T | 0.1719 | 0.94 (0.86 to 1.03) | 3.99E−07 | 0.79 (0.72 to 0.87) |
| rs1678536 | G | 0.7964 | 0.99 (0.88 to 1.1) | 9.86E−05 | 0.8 (0.72 to 0.9) |
| rs7313599 | G | 0.1479 | 1.06 (0.98 to 1.15) | 6.20E−05 | 0.82 (0.74 to 0.9) |
| rs1078109 | A | 0.09391 | 1.15 (0.98 to 1.35) | 1.42E−06 | 0.8 (0.73 to 0.88) |
| rs7305391 | A | 0.2615 | 0.95 (0.87 to 1.04) | 6.29E−07 | 0.8 (0.73 to 0.87) |
| rs1564374 | G | 0.2487 | 0.95 (0.86 to 1.04) | 0.000759 | 0.83 (0.74 to 0.93) |
| rs11172290 | G | 0.634 | 0.98 (0.88 to 1.08) | 4.10E−07 | 0.79 (0.73 to 0.87) |
| rs3825078 | A | 0.589 | 1.03 (0.93 to 1.14) | 1.36E−05 | 0.78 (0.7 to 0.87) |
| rs701006 | A | 0.4727 | 0.96 (0.85 to 1.08) | 0.003056 | 0.82 (0.72 to 0.94) |
| rs2301551 | G | 0.1587 | 0.88 (0.75 to 1.05) | 0.1069 | 0.88 (0.75 to 1.03) |
| rs12307841 | C | 0.6206 | 1.03 (0.91 to 1.17) | 1.23E−06 | 0.8 (0.73 to 0.87) |
| rs12368653 | G | 0.5573 | 1.03 (0.93 to 1.14) | 1.74E−05 | 0.78 (0.69 to 0.87) |
| rs1048691 | T | 0.795 | 1.01 (0.92 to 1.11) | 1.80E−06 | 0.8 (0.72 to 0.87) |
| rs6581155 | G | NA | NA | NA | NA |
Results for models assuming additive effects.
*Denotes results adjusted for rs6581155.
†Denotes results adjusted for locus tested.
NA, not applicable.