A | B | C | D | E | F | G | |
---|---|---|---|---|---|---|---|
Gender | Female | Female | Male | Male | Female | Male | Male |
RASopathy | NF1 | NF1 | NF1 | NF1 | CS | CFC | NS |
SCQ | 2 | 14 | 32* | 17* | 6 | 24* | 6 |
SRS | 46 | 73* | 108† | 92† | 79† | 87† | 64* |
IQ | |||||||
Verbal | 98 | 70‡ | 57‡ | 135 | 55‡ | 71 | 100 |
Performance | 102 | 67‡ | 67‡ | 98 | 59‡ | 65‡ | 142 |
Full IQ | 109 | 66‡ | 59‡ | 117 | 54‡ | 74 | 122 |
Vineland-II | |||||||
Communication | – | – | 67§ | 77 | 80 | 36§ | 106 |
Daily living skills | – | – | 59§ | 63§ | 47§ | 21¶ | 97 |
Socialisation | – | – | 50§ | 57§ | 67§ | 20¶ | 108 |
ADOS | |||||||
Communication | 1 | 0 | 5† | 2* | 4* | 4† | 1 |
Reciprocal social interaction | 1 | 1 | 12† | 6† | 15† | 11† | 2 |
Imagination/creativity | 0 | 0 | 1 | 2 | 1 | 1 | |
Restricted, repetitive behaviors | 0 | 0 | 2 | 2 | 0 | 2 | 0 |
ADOS classification | Non-ASD | Non-ASD | Autism | ASD | Autism | Autism | Non-ASD |
ADI-R | |||||||
Reciprocal social interaction | 0 | 1 | 29† | 18† | 18† | 21† | 2 |
Communication | 2 | 5 | 22† | 1 | 7 | 17† | 4 |
Restricted, repetitive behaviors | 0 | 0 | 3† | 2 | 3† | 7† | 2 |
Developmental abnormality | 1† | 0 | 5† | 1† | 5† | 3† | 1† |
Clinical impression | Non-ASD | Social anxiety | Autism | Autism spectrum | Atypical autism | Autism | Non-ASD |
Scores for ADOS, ADI-R and IQ tests for participants in in-person assessment.
*Meets threshold for ASD.
†Meets threshold for autism.
‡IQ is in the range of mild cognitive delay (55–70).
§Mild-moderate deficit (36–70).
¶Severe deficit (20–34).
ADOS, autism diagnostic observation schedule; ASD, autism spectrum disorder; CFC, cardio-facio-cutaneous syndrome; CS, Costello syndrome; NF1, neurofibromatosis type 1; NS, Noonan syndrome; SCQ, Social Communication Questionnaire; SRS, Social Responsiveness Scale.