Table 1

Target NGS statistics for 179 patients

Per base coverage62
% Target bp covered ≥1×97
% Target bp covered ≥10×84
% Target bp covered ≥20×70
Total number of variants (SNPs and indels)407
Rare variants24
Rare variants that lead to protein coding change:8.23
 Missense change3.81
 Nonsense change0.28
 Splicing site change0.15
 Non-frameshift indels1.56
 Frameshift indels2.46

  • All the values are the mean number derived from 179 patients.

  • NGS, next generation sequencing; SNPs, single nucleotide polymorphisms.