Table 1

Results of pathway enrichment analysis of the ISC dataset

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  • Pathways in grey are from the classes ‘immune system diseases’ or ‘immune system’ in the KEGG database.

  • *The pathway is also within the top 10 pathways in the corresponding scenario using cut-off 0.01.

  • †The pathway is also within top 10 in the corresponding scenario by both gene- and LD-clustered adjustment in MHC.

  • BH, multiple testing correction by Benjamini and Hochberg (1995); gamGWAS, generalised additive model for genome-wide association studies; KEGG, Kyoto Encyclopedia of Genes and Genomes; SNP, single-nucleotide polymorphism.