Table 4

Independent statistical evidence summarising support for the Chr 13q locus at ABCC4

NAnalysisp Value
Linkage results26 pedigreesLinkage5.41×10−5
LD mapping in case–controls191 cases, 225 controlsCase–control0.0021
LD mapping in Trios715 complete triosTDT0.0033
All LD mapping resultsFisher's test8.8×10−5
Addition of WTCCC controls4674Case–control<1.0×10−7
  • WTCCC controls were added to the case–control sample and re-analysed.

  • LD, linkage disequilibrium; TDT, transmission disequilibrium test; WTCCC, Wellcome Trust Case Control Consortium.