Family 1 - c.4403_4406delCTCT |
Proband | Pleuropulmonary blastoma | 1.5 | 5 |
Parent | None | | 40 |
Uncle | None | | 44 |
Grandparent | None | | 68 |
Family 2 - c.1716delT |
Proband | Pleuropulmonary blastoma | 0.8 | 2 |
Parent | None | | 36 |
Family 3 - c.1196_1197dupAG |
Proband | Pleuropulmonary blastoma | 4 | 5 |
Parent | None | | 30 |
Aunt | None | | 26 |
Grandparent | None | | 62 |
Family 4 - c.3505delT |
Proband | Pleuropulmonary blastoma | 3 | 3 |
Sibling | None | | 12 |
Parent | None | | 36 |
Family 5 - c.1966C>T p.R656X |
Proband | Pleuropulmonary blastoma | 7 | 12 |
Parent | None | | 52 |
Family 6 - c.2268_2271delTTTG |
Proband | Pleuropulmonary blastoma | 0.9 | 1 |
Parent | None | | 38 |
Family 7 - c.3665delT |
Proband | Pleuropulmonary blastoma* | 4.2 | died 5.2 |
Parent | None | | 36 |
Family 8 - c.3583_3584delGA |
Proband | Pleuropulmonary blastoma | 1.3 | 7 |
| Intraocular medulloepithelioma | 6 | |
parent | None | | 29 |
Family 9 - c.2040+1 G>C |
Proband | Pleuropulmonary blastoma | 3 | 13 |
Parent | Thyroid cysts unclassified | 25 | 38 |
Family 10 - c.3726C>A p.Y1242X |
Proband | Pleuropulmonary blastoma | 4 | 15 |
Parent | Thyroid cysts unclassified | 30 | 37 |
Family 11 - c.5465A>T p.D1822V† |
Proband | Pleuropulmonary blastoma | 1.8 | 9 |
Parent | Thyroid cysts unclassified | 20 | 40 |
Family 12 - c.3288_3289insTTTC |
Proband | Cystic nephroma | 1.5 | 11 |
Half-sibling | Cystic nephroma | 0.8 | 5 |
Parent | Multinodular colloid goitre | 25 | 39 |
Family 13 - c.328_338dupGTGTCAGCTGT |
Proband | Cystic nephroma | 3 | 5 |
Parent | Multinodular colloid goitre | 20 | 35 |
| Thyroglossal duct cyst | 30 | |
Grandparent | Thyroid cysts unclassified | 7 | 66 |
Great-aunt | None | | 59 |
Family 14 - c.5122_5128delGGAGATG |
Proband | Ovarian Sertoli–Leydig cell tumour L | 17 | 35 |
| Ovarian Sertoli–Leydig cell tumour R | 27 | |
Parent | Ovarian Sertoli–Leydig cell tumour R | 21 | 71 |
| Melanoma | 50 | |
| Endometrial cancer | 62 | |
| Breast cancer | 68 | |
Family 15 - c.1966C>T_p.R656X |
Proband | Ovarian Sertoli–Leydig cell tumour R | 12 | 17 |
| Ovarian Sertoli–Leydig cell tumour L | 14 | |
Parent | None | | 50 |
Family 16 - c.3793delA |
Proband | Ovarian sex cord stromal tumour R | 6 | 9 |
Parent | None | | 29 |
Family 17 - c.2988-2_2988-1delAGinsCT |
Proband | Wilms tumour | 8 | 15 |
| Multinodular thyroid goitre unclassified | 9 | |
| Ovarian Sertoli–Leydig cell tumour R | 12 | |
| Ovarian Sertoli–Leydig cell tumour L | 12 | |
Parent | None | | 40 |
Family 18 - c.1153delC |
Proband | Medulloblastoma/infratentorial PNET | 13 | 18 |
Family 19 - c.4740G>T p.Q1580H |
Proband | Seminoma | 32 | 46 |